Manchester United and Liverpool failed to produce a goal in a war of attrition that was low on quality at Old Trafford despite an intense build up.
The point moved Liverpool to the top of the Premier League, a single point clear of champions Manchester City.
The home side will be more satisfied with their work however, as Ole Gunnar Solskjaer was forced to make all three substitutions before half-time.
The Red Devils came close to stealing the win when Joel Matip turned into his own net, only for the offside flag to save Liverpool.
Good set up play from Romelu Lukaku had sent Jesse Lingard through on goal in the first half, but Alisson was razor-sharp in getting down at his feet to nick the ball from his toe.
David de Gea meanwhile kept the 100th clean sheet of his Premier League career with scarcely a moment of worry.
United lost Ander Herrera and Juan Mata to injury before 25 minutes had elapsed and then Lingard – on for the latter – had to make way for Alexis Sanchez before half-time having succumbed to injury.
In the circumstances, Solskjaer was content with his team, especially as Marcus Rashford also appeared to be labouring for the entire second half.
"Everything that could have gone wrong in the first half went wrong. We had four injuries – we had to keep Marcus Rashford on – it seemed like it was going to be a tough afternoon," said the United boss.
"I can't remember Liverpool having a chance. Even though they had possession, I can't remember David de Gea making a save.
Roberto Firmino also went off injured during a stop-start first half, something Jurgen Klopp felt disrupted the game. The Liverpool manager ultimately conceded it was a chance missed.
"It was a strange game. We started really well. All the injuries in the game obviously cost us rhythm. It happened to us with 'Bobby' and that was a catastrophe," he said.
"United played with a completely new midfield and three up front. We lost our rhythm and couldn't get it back.
"It was a game without a lot of highlights – it was intense. On days when United are beatable you have to do it and we didn't do it."
Liverpool are now 13/8 to win the title, with Man City 8/15 to defend their crown. Man United meanwhile are 13/10 to win at Crystal Palace on Wednesday evening.
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