Tottenham Hotspur midfielder Moussa Sissoko is facing around a fortnight on the sidelines due to a groin strain sustained in the Champions League clash with Manchester City last week.
The 29-year-old France international had to be replaced just before half-time of a 4-3 defeat which was still enough for Spurs to reach the semi-finals in Europe, where they will face Ajax.
Sissoko sat out the subsequent 1-0 Premier League reverse to the Citizens last Saturday and is a definite absentee for the league visit of Brighton to the Tottenham Hotspur Stadium on Tuesday evening.
Head coach Mauricio Pochettino also confirmed that late decisions will be taken on midfielder Harry Winks and goalkeeper Hugo Lloris for the clash with the Seagulls, but it is Sissoko who is his main concern.
He told reporters: "Moussa Sissoko is not going to be fit, maybe for the next two weeks. We hope he can recover before, but I am not so optimistic."
Meanwhile, Pochettino is confident that his players will not lose focus for the job of securing a top-four league finish, despite the looming prospect of their Champions League last-four tie.
He added: "We are not thinking of Ajax. We showed at Manchester City that we are thinking in the now and this competition, the Premier League.
"Now our energy is in Brighton. It is so clear that we have two objectives – one is to be in the top four at the end of the season and the other is to beat Ajax, but we need to go step-by-step.
"The players, they know it. I think their behaviour and mentality is perfect."
Spurs are available at 4/11 to defeat Brighton on Tuesday evening and are 11/2 to do so by a 2-0 scoreline, with Son Heung-Min 1/1 to score at any time in the game.
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